Tapping on Mutant Human Ruperts in Quahog gives you the option to lower their Health Points with the help of the following characters:
- Stereo Head Peter
- Countess Lois (Character)

Each try requires 2 Antiviruses and you can use up to two characters at once. When the Mutant Human Ruperts’’s Health Points go to Zero, they will be cleared.

During attempts to clear Mutant Human Ruperts, your team also takes damage and tries to dodge. Occasionally, attempts to ward may be successful. Once your character’s Health Points becomes zero, they will begin to heal their Health Points over time or they can be instantly healed to full Health Points using Clams.